Mechanism · Dosing · Effects

Overview

GHK-Cu is a naturally occurring copper peptide known for its regenerative and cosmetic benefits. It is commonly used to support skin repair, collagen production, wound healing, and overall tissue recovery. Administration is typically done subcutaneously in small daily doses.

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Mechanism (how it works)

• Copper delivery: Provides bioavailable copper, a key cofactor for enzymes involved in tissue remodeling.

• Collagen & elastin stimulation: Enhances structural protein production to improve skin firmness and elasticity.

• Tissue repair: Accelerates wound healing, cell turnover, and overall regenerative processes.

• Anti-inflammatory action: Modulates inflammation and supports recovery.

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Dosing & Protocol (practical)

Goal: Skin regeneration, tissue repair, recovery enhancement
Route: Subcutaneous injection
Cycle length: 8–12 weeks, followed by a 30-day rest

Vial / Reconstitution Example

50 mg vial + 3.0 mL bacteriostatic water → ~16.7 mg/mL

• 1 mg ≈ 0.06 mL → ~6 units

• 2 mg ≈ 0.12 mL → ~12 units

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Protocol A — Standard Daily Protocol

Daily injection (once per day)

• Weeks 1–4: 1 mg daily (~6 units)

• Weeks 5–8: 2 mg daily (~12 units)

• Weeks 9–12 (optional): Maintain 2 mg daily

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Protocol B — 5 Days On / 2 Days Off (Higher dose option)

2 mg per injection (Mon–Fri)
Weekend off (Sat–Sun)

• Inject 2 mg (~12 units) once daily

• Use Monday to Friday on, Saturday–Sunday off

• Continue for 8–12 weeks

This protocol reduces injection frequency while maintaining high regenerative support.

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Effects & Benefits

• Improved skin texture, tone, and firmness

• Enhanced wound healing and tissue repair

• May support hair health and recovery post-procedure

• Reduced inflammation and faster recovery from stressors

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Side Effects & Safety Notes

Common (mild):

• Injection-site redness, mild irritation

Less common:

• Headache (rare)

Action:
Stop use and seek medical guidance if experiencing unusual or severe symptoms.

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