Mechanism · Dosing · Effects (10 mg protocol)

Overview

BPC-157 is a synthetic peptide widely referenced for supporting tissue repair, recovery from soft-tissue injuries, and gastrointestinal protection. It is typically used daily via subcutaneous or intramuscular injection. This guide provides a practical 10 mg vial-based dosing & reconstitution protocol and key clinical notes.

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Mechanism (how it works)

Tissue Repair Activation

• Promotes angiogenesis (new blood vessel formation)
• Enhances fibroblast activity → improved collagen formation
• Supports tendon, ligament, joint, and muscle repair

Gastrointestinal Protection

• Helps maintain and repair the gut lining
• May reduce inflammation in the GI tract

Anti-inflammatory Effects

• Downregulates inflammatory cytokines
• Supports faster recovery from mechanical stress and injury

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Dosing & Reconstitution Guide (practical)

Route: Subcutaneous or intramuscular
Frequency: 1–2× daily
Cycle Length: 4–8 weeks (some extend to 12 weeks)
Storage:
• Lyophilized vial: freezer
• Reconstituted vial: refrigerator (2–8 °C), protected from light

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Reconstitution Options

Standard / Gradual Approach (3 mL → ~3,333 mcg/mL)

10 mg vial + 3.0 mL bacteriostatic water → ~3,333 mcg per mL

Conversions:
• 0.1 mL = ~333 mcg
• 0.03 mL (~9 units on insulin pin) = ~300 mcg
• 0.045 mL (~15 units) = ~500 mcg

Example Titration (Moderate Protocol)

Weeks 1–4: 300 mcg once daily (~9 units)
Weeks 5–8: 500 mcg once daily (~15 units)

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Advanced / Aggressive Approach (2 mL → ~5,000 mcg/mL)

10 mg vial + 2.0 mL bacteriostatic water → ~5,000 mcg per mL

Conversions:
• 0.1 mL = 500 mcg
• ~10 units = ~500 mcg
• ~15 units = ~750 mcg

Example Titration (Advanced Protocol)

Weeks 1–4: 500 mcg, 2× daily (~10 units each)
Weeks 5–8: 750 mcg, 2× daily (~15 units each)

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Effects & Benefits

Injury Recovery

• Supports tendon, ligament, joint, and muscle repair
• May accelerate post-injury healing

Gastrointestinal Support

• Potential protection and repair of the stomach & intestinal lining

Inflammation Reduction

• Often noted to reduce pain/inflammation around injured tissue

General Recovery

• Faster recovery from training
• Improved tissue resilience

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Side Effects & Safety Notes

Common:
• Mild headache
• Injection-site irritation
• Occasional nausea

Important Notes:
• Long-term human data is limited
• Avoid contaminated or low-quality peptides
• Theoretical angiogenesis risks → avoid if you have cancer or suspicious masses
• Always monitor response during use

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